Project
EF4-7
The Impact of Dormancy on the Evolutionary, Ecological and
Pathogenic Properties of Microbial Populations
Project Heads
Jochen Blath, Maite Wilke Berenguer
Project Members
Tobias Paul (HU)
Project Duration
01.04.2021 − 31.03.2024
Located at
HU Berlin
Description
Dormancy is an ubiquitous trait in microbial communities. It describes the ability of an organism to switch into a metabolically inactive and protected state, for example in response to environmental stress. Dormancy has important implications for the evolutionary, ecological and pathogenic character of microbial systems. This project derives and analyses new stochastic individual based models for the dynamics of dormancy-exhibiting biological systems.
We pursue two larger goals: On one hand, we aim to understand the influence of dormany on patterns of genetic diversity through the tools of population genetics, deriving as scaling limits from individual based models dual pairs of processes of diffusions and coalescents that incorporate feaures such as varying population size.
On the other hand we study invasion, fixation and coexistence regimes withing the framework of adaptive dynamics, again, based on individual based models and there many particle limits.
External Website
Related Publications
- Principles of seed banks and the complexity emerging from dormancy, Nature Communications 12, 4807, (2021)
J. T. Lennon, F. den Hollander, M. Wilke Berenguer, J. Blath - The interplay of dormancy and transfer in bacterial populations: Invasion, fixation and coexistence regimes, Theoretical Population Biology 139, 18-49, (2021)
J. Blath, A. Tóbiás - Virus dynamics in the presence of contact-mediated host-dormancy, preprint (2021)
J. Blath, A. Tóbiás - A stochastic adaptive dynamics model for bacterial populations with mutation, dormancy and transfer, preprint (2021)
J. Blath, T. Paul, A. Tóbiás. - Lambda-coalescents arising in populations with dormancy, Electronic Journal of Probability 27, (2022)
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