EF3 – Model-Based Imaging



Model-based 4D reconstruction of subcellular structures

Project Heads

Peter Hiesinger, Max von Kleist, Steffen Prohaska, Martin Weiser

Project Members

David Knötel (ZIB)

Project Duration

01.01.2019 – 31.12.2021

Located at



Modern two-photon microscopy allows to acquire unprecedented amounts of time-resolved 4D image data during cellular development. Segmentation is required to identify and track single objects over time for downstream analysis and model building. We aim at quasi-automatic parameterized segmentation based on geometric and dynamic priors.

Selected Publications

Selected Pictures

Combining microscopy data and growth dynamics models into a model based filopodia reconstruction loop.

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