Project
AA1-1
The spatio-temporal modelling of mechanisms underlying pain relief via the µ-opioid receptor
Project Heads
Martin Lohse, Marcus Weber, Christof Schütte, Christoph Stein
Project Members
Vikram Sunkara (FU), Noureldin Saleh (ZIB)
Project Duration
01.01.2019 – 31.12.2021
Located at
FU Berlin / ZIB
Description
Opioid receptors play a major role in the treatment of severe pain. The project aims at accurate spatio-temporal modelling and simulation of intracellular signaling cascades initiated by opioid receptors, such as G-proteins, ion channels, cAMP, and the arrestin complex in order to design, e.g., non-addictive pain treatments.
Project Webpages
Selected Publications
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