AA1 – Life Sciences

Project

AA1-1

The spatio-temporal modelling of mechanisms underlying pain relief via the µ-opioid receptor

Project Heads

Martin Lohse, Marcus Weber, Christof Schütte, Christoph Stein

Project Members

Vikram Sunkara (FU), Noureldin Saleh (ZIB)

Project Duration

01.01.2019 – 31.12.2021

Located at

FU Berlin / ZIB

Description

Opioid receptors play a major role in the treatment of severe pain. The project aims at accurate spatio-temporal modelling and simulation of intracellular signaling cascades initiated by opioid receptors, such as G-proteins, ion channels, cAMP, and the arrestin complex in order to design, e.g., non-addictive pain treatments.

Project Webpages

Selected Publications

Selected Pictures

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